EXPRESSION OF DNAJB12 OR DNAJB14 CAUSES COORDINATE INVASION OF THE NUCLEUS BY MEMBRANES ASSOCIATED WITH A NOVEL NUCLEAR PORE STRUCTURE.

Expression of DNAJB12 or DNAJB14 causes coordinate invasion of the nucleus by membranes associated with a novel nuclear pore structure.

DNAJB12 and DNAJB14 are transmembrane proteins in the endoplasmic reticulum (ER) that serve as co-chaperones for Hsc70/Hsp70 heat shock proteins.We demonstrate that over-expression of DNAJB12 or DNAJB14 causes the formation of elaborate membranous structures within cell nuclei, which we designate DJANGOS for DNAJ-associated nuclear globular structu

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Investigation of relationship between Job fatigue,Organizational citizenship Behavior and Organizational Atmosphere

This study aims to consider the relationships between job fatigue, organizational citizenship behavior and organizational atmosphere.The evaluation of each variable is a kind of decision making problem which Metal Keychain has systematic transaction between variables.So, Decision making trial and evaluation laboratory (DEMATEL) is suitable for defi

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Exploring the causal role of pathogen-derived antibodies in major urinary and kidney diseases: Insights from generalized summary data-based Mendelian randomization

Chronic kidney Ball - Glove Batting - Junior and urinary tract diseases, including glomerulonephritis, nephrotic syndrome, and chronic kidney disease (CKD), present significant global health challenges.Recent studies suggest a complex interplay between infectious pathogens and immune-mediated kidney damage.This study employs Generalized Summary dat

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Modeling Carbon Budgets and Acidification in the Mediterranean Sea Ecosystem Under Contemporary and Future Climate

We simulate and analyze the effects of a high CO2 emission scenario on the Mediterranean Sea biogeochemical state at the end of the XXI century, with a focus on carbon cycling, budgets and fluxes, within and between the Mediterranean sub-basins, and on ocean acidification.As a result of the overall warming of surface water and exchanges at the boun

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